姓 名：徐龙

联系地址：浙江省宁波市镇海区毓秀路505号宁波大学北校区1号实验楼502

电子邮件：xulong@daohangbc.com

个人基本信息：男，讲师；2018年6月毕业于四川大学-国家生物材料工程技术研究中心，获生物医学工程专业博士学位，同年7月加入博彩导航-大陆博彩网站 ，从事生物医用材料、纳米药物递送系统及医用小分子凝胶的研发工作。

研究领域：1）功能性纳米载药系统及其在癌症、炎症等领域的研究应用 2）生物医用高分子的设计合成及其应用 3）激响应性小分子凝胶载体的设计合成及应用

研究项目：

1.深层渗透阻断胰腺导管腺癌内神经支配的纳米载药系统，国家自然科学基金-青年基金（2022-2024）；

2.靶向碳酸酐酶XI促进低氧肿瘤转胞吞渗透的新型纳米药物递送系统，浙江省自然科学基金-青年项目（2021-2023）；

3.靶向肿瘤微环境髓源抑制细胞的pH敏感性新型纳米药物传输系统用于癌症免疫治疗的研究，宁波市自然科学基金青年项目（2019-2020）。

研究成果：（2017年至今）

1. Caidie Xu,Long Xu*, Renlu Han, Yabin Zhu, Jianfeng Zhang*, Blood circulation stable doxorubicin prodrug nanoparticles containing hydrazone and thioketal moieties for antitumor chemotherapy.Colloids and Surfaces B: Biointerfaces.2021, 201, 11163.

2. Renyuan Chen, Caidie Xu, Yihao Lei, Hongxin Liu*, Yabin Zhu, Jianfeng Zhang andLong Xu*, Facile construction of a family of supramolecular gels with good levofloxacin hydrochloride loading capacity.RSC Advances.2021, 11, 12641–12648.

3. Caidie Xu, Renlu Han, Hongxin Liu,* Yabin Zhu, Jianfeng Zhang, andLong Xu*, Construction of polymeric micelles for improving cancer chemotherapy by promoting the production of intracellular reactive oxygen species and self-accelerating drug release.ChemistrySelect.2021, 6, 3277–3285.

4. Long Xu, Mingying Zhao, Wenxia Gao⁎, Yidi Yang, Jianfeng Zhang, Yuji Pu，Bin He*. Polymeric nanoparticles responsive to intracellular ROS for anticancer drug delivery.Colloids and Surfaces B: Biointerfaces.2019, 181, 252–260.

5. Long Xu, Mingying Zhao, Hai Zhang, Wenxia Gao*, Zhaoyuan Guo, Xuequan Zhang, Jianfeng Zhang, Jun Cao, Yuji Pu, and Bin He*. Cinnamaldehyde-Based Poly(ester-thioacetal) To Generate Reactive Oxygen Species for Fabricating Reactive Oxygen Species Responsive Nanoparticles.Biomacromolecules.2018, 19, 4658-4667.

6. Long Xu, Yidi Yang, Mingying Zhao, Wenxia Gao*, Hai Zhang, Sai Li, Bin He and Yuji Pu*. A reactive oxygen species–responsive prodrug micelle with efficient cellular uptake and excellent bioavailability.Journal of Materials Chemistry B.2018, 6, 1076-1084.

7. Long Xu, Mingying Zhao, Yidi Yang, Yan Liang, Changzhen Sun, Wenxia Gao,* Sai Li, Bin He and Yuji Pu*. A reactive oxygen species (ROS)-responsive low molecular weight gel co-loaded with doxorubicin and Zn(II) phthalocyanine tetrasulfonic acid for combined chemo-photodynamic therapy.Journal of Materials Chemistry B.2017, 5, 9157-9164.

8. Long Xu#, Yan Liang#, Changzheng Sun, Na Hao, Jianqin Yan, Wenxia Gao*, Bin He*. Substitution of Percutaneous Ethanol Injection with a Low Molecular Weight Peptide Gel Mimicking Chemoembolization for Cancer Therapy.Nanotheranostics.2017, 1, 313-325.